Hong Kong Journal of Nephrology
Volume 7, Issue 1 , Pages 22-26 , April 2005

Effects of a Tolerance Induction Protocol in Renal Allograft Recipients — the Ahmedabad Experience

  • Aruna V. Vanikar

      Affiliations

    • Department of Immunohematology, Institute of Kidney Diseases & Research Centre and Institute of Transplantation Sciences, Ahmedabad, India
    • Department of Pathology, Laboratory Medicine and Transfusion Services, Institute of Kidney Diseases & Research Centre and Institute of Transplantation Sciences, Ahmedabad, India
    • Corresponding Author InformationAddress correspondence and reprint requests to: Dr. Aruna V. Vanikar, Department of Pathology, Laboratory Medicine and Transfusion Services, and Department of Immunohematology, Institute of Transplantation Sciences, Civil Hospital Campus, Asarwa, Ahmedabad 380-016, Gujarat, India. Fax: (+91) 79-2268-5454
  • ,
  • Hargovind L. Trivedi

      Affiliations

    • Department of Transplantation Medicine and Nephrology, Institute of Kidney Diseases & Research Centre and Institute of Transplantation Sciences, Ahmedabad, India
  • ,
  • Rashmi D. Patel

      Affiliations

    • Department of Pathology, Laboratory Medicine and Transfusion Services, Institute of Kidney Diseases & Research Centre and Institute of Transplantation Sciences, Ahmedabad, India
    • Department of Immunohematology, Institute of Kidney Diseases & Research Centre and Institute of Transplantation Sciences, Ahmedabad, India
  • ,
  • Kamal V. Kanodia

      Affiliations

    • Department of Pathology, Laboratory Medicine and Transfusion Services, Institute of Kidney Diseases & Research Centre and Institute of Transplantation Sciences, Ahmedabad, India
    • Department of Immunohematology, Institute of Kidney Diseases & Research Centre and Institute of Transplantation Sciences, Ahmedabad, India
  • ,
  • Javed M. Vakil

      Affiliations

    • Department of Transplantation Medicine and Nephrology, Institute of Kidney Diseases & Research Centre and Institute of Transplantation Sciences, Ahmedabad, India

References 

  1. Trivedi HL , Shah VR , Shah PR , Darji PI , Sane AS , Vanikar AV , et al.   High dose PBSC associated tolerance in live-related renal allograft recipients . Transplant Proc . 2000;32:2001–2002
  2. Trivedi HL , Shah VR , Shah PR , Sane AS , Vanikar AV , Trivedi VB , et al.   Megadose approach to DBMC infusion-induced allograft hyporesponsiveness in living-related renal allograft recipients . Transplant Proc . 2001;33:71–76
  3. Trivedi HL , Shah VR , Vanikar AV , Gera DN , Shah PR , Trivedi VB , et al.   High-dose peripheral blood stem cell infusion: a strategy to induce donor-specific hyporesponsiveness to allografts in pedia-tric renal transplant recipients . Pediatr Transplant . 2002;6:63–68
  4. Trivedi H , Vanikar A , Shah V , Mehta A , Shah S , Shah T , et al.   Mega dose unfractionated donor bone marrow-derived cell infusion in thymus and periphery - an integrated clinical approach for tolerance in live related renal allografts . Transplant Proc . 2003;35:203–206
  5. Racusen LC , Solez K , Colvin RB , Bonsib SM , Castro MC , Cavallo T , et al.   The Banff 97 working classification of renal allograft pathology . Kidney Int . 1999;55:713–723
  6. Calne RY . Cyclosporin in cadaveric renal transplantation: 5-year follow-up of a multicentre trial . Lancet . 1987;2:506–507
  7. Remuzzi G , Perico N . Cyclosporine-induced renal dysfunction in ex-perimental animals and humans . Kidney Int Suppl . 1995;52:S70–S74
  8. Sibley RK , Rynasiewicz J , Ferguson RM , Fryd D , Sutherland DE , Simmons RL , et al.   Morphology of cyclosporine nephrotoxicity and acute rejection in patients immunosuppressed with cyclo-sporine and prednisone . Surgery . 1983;94:225–234
  9. Min DI . Cyclosporine. . In:  Schumacher D editors. Therapeutic Drug Monitoring. . Stanford, CT: Appleton and Lange; 1995;p. 449

PII: S1561-5413(09)60176-9

doi: 10.1016/S1561-5413(09)60176-9

Hong Kong Journal of Nephrology
Volume 7, Issue 1 , Pages 22-26 , April 2005